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OHN Educational Activities and Resources

MWAOHN posts educational activities of interest to occupational health nurses. To have your activity posted, please send a message to the Webmaster.

MWAOHN makes no guarantees on any educational activities posted on this website.

All previous OHN Educational articles have been moved to the Archives OHN Educational.  Mouse over the Archives OHN Educational in the left navigation and a list of archived articles will appear.


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May 22, 2010

Occupational and Environmental Medicine Conference: Genetics in the Workplace

Registration/Information:  http://www.jhsph.edu/erc/MCOEMupdate.html

Please join us for our Spring Occupational Safety and Health Conference, "Genetics in the Workplace: Science, Medicine, Legislation and Regulation... How does it all connect?"," scheduled on Saturday, May 22, 2010 at the Johns Hopkins Bloomberg School of Public Health in Baltimore, MD.

Recent advances in the field of genetics and passage of the new Genetic Information and Non-discrimination Act (GINA) are already impacting workplace safety and health programs.  The upcoming conference will feature presentations in the area of genetics, law and policy and provide an opportunity to discuss how your practice or program may be impacted. 

We would like to give you an opportunity to ask questions during this session. We invite you to send in your questions before the conference to John Piacentino (johnpiacentino@msn.com) or bring your questions with you.  Finally, if you know of an early career occupational safety and health professional, please invite them to attend.


Keith Choi  kchoi@jhsph.edu

Program Coordinator  ERC Continuing Education

Johns Hopkins Bloomberg School of Public Health

615 North Wolfe Street, Room W7517 Baltimore, MD 21205

(410) 955-4088      (410) 614-4986 Fax

Visit us on the web: http://www.jhsph.edu/erc/ce  


Patients Shouldn't Navigate Internet Without Physician

Date: 3/24/2010
BIDMC Contact: Jerry Berger
Phone: 617-667-7308
Email: jberger@bidmc.harvard.edu

BOSTON - The Internet has had a profound effect on clinical practice by providing both physicians and patients with a wealth of information. But with those rewards come risks of incorrect or poorly interpreted information that require that a doctor "never be optional.""

http://www.bidmc.org/News/InMedicine/2010/March/GroopmanHartzbandNEJM.aspx



Surgical Masks Provided Effective Protection of Health-Care Workers Against H1N1, Study Suggests

ScienceDaily (Mar. 29, 2010)  The effectiveness of ordinary surgical masks as opposed to respirators in protecting health care workers against the 2009 H1N1 influenza virus has been the subject of debate. An observational study published in the April 1, 2010 issue of Clinical Infectious Diseases, available online, suggests that surgical masks are just as effective as respirators in this regard.  Read more:  http://www.sciencedaily.com/releases/2010/03/100325143055.htm


Chemical Exposure Before Mid-30s May Be Critical in Breast Cancer Development

ScienceDaily (Apr. 1, 2010)  Occupational exposure to certain chemicals and pollutants before a woman reaches her mid-30s could treble her risk of developing cancer after the menopause, suggests research published in Occupational and Environmental Medicine.  Read more:  http://www.sciencedaily.com/releases/2010/03/100331201539.htm


Desk Ergonomics Seminar presented by Stephen Sarro

Thank you to Stephen Sarro for helping us understand that desk work can cause injury to some people.  The way a work station is configured can cause injury and disability to the spine and extremities. Stephen explained to us, with demonstration and hands-on practice, how to assess the individual for potential nerve and muscle stressors, and to set up a desk for the best possible bio-mechanics.  Stephen met his goal that we left this one hour lecture more confident in our ability to  perform ergonomic assessments. 

Contact Stephen for training or ergonomic assessments:  stephen.sarro@ssptdc.com
Sports and Spinal Physical Therapy


Stephen Sarro, PT OMT
Assessing potential neck muscle involvement
Assessiong potential arm nerve involvement
 

White rye bread leads to better insulin and blood sugar levels


Research at the Lund University Faculty of Engineering shows that bread baked with white rye flour, which is flour made from the inner, white part of the rye kernel, leads to better insulin and blood sugar levels compared with wheat bread with rye bran.
Read more:  http://www.sciencedaily.com/releases/2010/02/100212210212.htm


New CDC Website:  Safe Healthcare


http://blogs.cdc.gov/safehealthcare/


CHEMICAL TERRORISM FOR THE CLINICIAN:
DETECTION, DIAGNOSIS & TREATMENT


DATE: This program is scheduled nine times in 2010!  FREE

Choose ONE: March 1, 2, 8, 12, 30; April 1, 6, 9, 12

TIME: 8:45 am - 2:30 pm

LOCATION: National Capital Poison Center
3201 New Mexico Avenue, NW, Suite 310
Washington, DC 20016

TO REGISTER:
E-mail to ferguson@poison.org
Call 202-362-3867 to request a registration form.

Visit www.poison.org and click on "Course Registration" to download a registration form.

Registrations will be confirmed by email. Directions will be sent with confirmation.

Programs fill quickly so do not assume you are registered unless you receive a confirmation.

FOR QUESTIONS: Contact Rennie Ferguson at 202-895-4263 or ferguson@poison.org.



Educational Information from CDC - joint venture with Department of Energy's Oak Ridge Institute for Science and Education

The Roadmap (http://www.cdc.gov/dhdsp/roadmap/index.htm ) is a step-by-step guide for HDSP public health practitioners in the systematic approach to developing a state-level HDSP program.  The steps are listed on the right hand side menu along with a link to resources and training, which you may especially find useful.

Web-based CDCynergy for Heart Disease and Stroke Prevention (http://www.cdc.gov/dhdsp/CDCynergy_training/) a self-guided tutorial on developing health communication campaigns related to heart disease and stroke prevention.

CDC/HDSP's home page (http://www.cdc.gov/dhdsp/index.htm) - this page will give you an overview of many of the resources available from CDC HDSP

CDC/HDSP's annual meeting page (http://www.orau.gov/hsc/hdspinstitute/ ) - ORISE provides technical assistance annually to CDC/HDSP's meeting which includes workshops and training on HDSP's program priorities.  We create this page after the meeting every year and post the informational and training materials from the meeting.

Want more info:

A.M. Lindsey, Group Manager, Health Training
Health and Safety Communications, MS -10
Oak Ridge Institute for Science and Education
PO Box 117
Oak Ridge, TN 37831-0117
865-576-2267 (6264 fax)
AM.Lindsey@orise.orau.gov

http://orise.orau.gov/training/index.htm 

www.orise.orau.gov/healthcomm

What's New in STD, HIV, Family Planning, and Addictions

Wednesday, March 24, 2010

8:30am - 3:45pm (registration begins at 8:00am)
No fee.  Lunch will be provided.

Location:
Kellogg Conference Center at Gallaudet University
800 Florida Avenue NE
Washington, DC 20002

Speakers:
Lisa Fitzpatrick, MD, MPH  Howard University

Carmen E. Greiner, MS, LPC, LSATP, MAC  Lighthouse Counseling

Mark Hathaway, MD, MPH  Washington Hospital Center

Anne Rompalo, MD, ScM  Johns Hopkins University

To Register Contact : 

Andrew D. Wheeler
Community Health Educator
Inova Juniper Program
Phone: 703-321-2903
Fax: 703-321-2603
andrew.wheeler@inova.org


Two Not-to-be-Missed Johns Hopkins Educational Programs!

JOHNS HOPKINS EDUCATION AND RESEARCH CENTER IN COOPERATION WITH THE NATIONAL INSTITUTE FOR OCCUPATIONAL SAFETY AND HEALTH, CENTERS FOR DISEASE CONTROL AND PREVENTION, U.S. DEPARTMENT OF HEALTH, AND HUMAN SERVICES PRESENT:

 PHYSICAL ASSESSMENT FOR NURSES
March 15 & 16, 2010
Johns Hopkins School of Nursing
525 N. Wolfe Street
Baltimore, MD 21205

This Course is Designed for all Nurses Who Desire:

  • To learn how to take an occupational health history
  • To learn normal and abnormal characteristics of the physical exam for the occupational setting
  • A hands-on course taught by experienced Johns Hopkins School of Nursing faculty

********************************************************


OVERVIEW OF OCCUPATIONAL HEALTH NURSING
March 17, 18 & 19, 2010
Johns Hopkins Bloomberg School of Public Health
615 North Wolfe Street
Baltimore, MD 21205

This Course is Designed for Occupational Health Nurses Who Desire:
  • Intensive Preparation for the ABOHN Certification Exam
  • In-depth Review of the Principles and Practice of Occupational Health Nursing
  • Comprehensive Course Study for Nurses New to the Field of Occupational Health

TO REGISTER:
Download a registration form at: www.jhsph.edu/erc/ce/ohnbrochure.html
or contact: Keith Choi, Program Assistant ERC Continuing Education
410-955-4088 (voice) 410-614-4986 (fax) or e-mail: kchoi@jhsph.edu

FACULTY:
Johns Hopkins faculty and associates.

FEE:
Includes course handouts, continental breakfasts, and refreshment breaks. Full-time JHU faculty, staff, and eligible dependents may enroll under the terms of the JHU Tuition Remission Program.

STUDY DISKS:
DataChem study disk available for purchase at discount rate of $150.

HOTELS:
Convenient hotels can be found on our web site: www.jhsph.edu/erc/ce - Click on "Baltimore Hotels"

TUITION:
* Course fee is $425 before March 1, $475 after March 1.

** Course fee is $495 before March 3, $545 after March 3.

Johns Hopkins reserves the right to cancel the course. Registration, less a $50 service charge, is returnable if written notice of cancellation is received two weeks prior to course start date.

No refunds will be issued for cancellations after that time. The full enrollment fee will be returned if the course is cancelled.



Visit our Website for information on other courses: http://www.jhsph.edu/erc/ce

 

Questions:

Mary Doyle, MPH, RN, COHN-S/CM

Director of ERC Continuing Education

mdoyle@jhsph.edu

410-955-0423


Hidden Health Hazards - At Home and Away

The world is a dangerously contaminated place. While you're certainly aware of many common health risks and germ factories, we went looking for less-known hazards that lurk where we sleep, eat and frolic.

Hotels and motels are among the leading culprits for spreading disease. In August 2009, media reports revealed that state inspectors from the Florida Division of Hotels and Restaurants, which includes the resort-happy city of Orlando, inspected 7,000 hotels and motels and found 27,000 health and safety violations.  Showerheads, doorknobs, drinking glasses, saunas, tubs, swimming pools, Tylenol overdose for hangovers, energy drinks, radiation risk from CT Scans, and more.

Read the entire list of culprits at:
http://snipurl.com/t92bw

NIAID Scientists Propose New Explanation for Flu Virus Antigenic Drift

Influenza viruses evade infection-fighting antibodies by constantly changing the shape of their major surface protein. This shape-shifting, called antigenic drift, is why influenza vaccines - which are designed to elicit antibodies matched to each year's circulating virus strains - must be reformulated annually. Now, researchers from the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, have proposed a new explanation for the evolutionary forces that drive antigenic drift. The findings in mice, using a strain of seasonal influenza virus first isolated in 1934, also suggest that antigenic drift might be slowed by increasing the number of children vaccinated against influenza.

Scott Hensley, Ph.D., Jonathan W. Yewdell, M.D., Ph.D., and Jack R. Bennink, Ph.D., led the research team, whose findings appear in the current issue of Science.  "Our model predicts that decreasing the immunologically naive population - by increasing the number of children vaccinated against influenza, for example - could slow the rate of antigenic drift and extend the duration of effectiveness of seasonal influenza vaccines," he says.

Reference: SE Hensley et al. Hemagglutinin receptor binding avidity drives influenza A virus antigenic drift. Science. DOI: 10.1126/science.1178258 (2009).

NOTE: An illustration depicting antigenic drift is available at: http://www3.niaid.nih.gov/topics/Flu/Research/basic/AntigenicDriftIllustration.htm

Read the full announcement at:  http://www.nih.gov/news/health/oct2009/niaid-29.htm


Study Shows How Nanotubes Affect Lining of Lungs

Tiny carbon nanotubes are being considered for use in everything from sports equipment to medical applications, but a great deal remains unknown about whether these materials cause respiratory or other health problems. Now a collaborative study from North Carolina State University, The Hamner Institutes for Health Sciences, and the National Institute of Environmental Health Sciences shows that inhaling these nanotubes can affect the outer lining of the lung, though the effects of long-term exposure remain unclear.

Using mice in an animal model study, the researchers set out to determine what happens when multi-walled carbon nanotubes are inhaled. Specifically, researchers wanted to determine whether the nanotubes would be able to reach the pleura, which is the tissue that lines the outside of the lungs and is affected by exposure to certain types of asbestos fibers which cause the cancer mesothelioma. The researchers used inhalation exposure and found that inhaled nanotubes do reach the pleura and cause health effects.  Inhaled carbon nanotubes accumulate within cells at the pleural lining of the lung as visualized by light microscopy.

Short-term studies described in the paper do not allow conclusions about long-term responses such as cancer. However, the inhaled nanotubes "clearly reach the target tissue for mesothelioma and cause a unique pathologic reaction on the surface of the pleura, and caused fibrosis," says Dr. James Bonner, associate professor of environmental and molecular toxicology at NC State and senior author of the study.

Read the story at:  http://news.ncsu.edu/releases/wmsbonnernanotubes/


New laryngoscope could make difficult intubations easier

AUGUSTA, Ga. - A new tool developed by a Medical College of Georgia resident and faculty member may make it easier to place assisted breathing devices under difficult circumstances.  About 2 percent of patients that undergo the process, called intubation, experience complications - regardless if it's performed in an emergency situation or prior to surgery. During normal intubation, a physician stands behind a patient's head and uses a metal scope to open the mouth and guide a flexible plastic tube into the trachea. The tube is used to maintain a patient's airway and provide a pathway for mechanical ventilation if necessary.  Difficult intubations can be traumatic for patients and lead to problems such as cracked teeth, he says.

To make those intubations easier, the physicians developed the Video Rigid Flexible Laryngoscope.   The device is the first of its kind to merge two technologies - video and articulation, he says. It's being used successfully at MCGHealth Medical Center and at other hospitals in California, North Carolina, Washington and Wisconsin.

Read more at:  http://www.eurekalert.org/pub_releases/2009-10/mcog-nlc101509.php


Pain In The Neck:  Too Much Texting Could Lead To Overuse Injuries

ScienceDaily (Nov. 10, 2009)  The world record for fastest text message typing is held by a 21-year old college student from Utah, but his dexterous digits could mean serious injury later on. Most adults aged 18-21 prefer texting over e-mail or phone calls, and ergonomics researchers are starting to wonder whether it's putting the younger generation at risk for some overuse injuries -- once reserved for older adults who have spent years in front of a computer.

Judith Gold, an assistant professor of Epidemiology at the College of Health Professions and Social Work, thinks this might be the case. At this year's annual meeting of the American Public Health Association, she presented preliminary research which suggested that among college students, the more they texted, the more pain they had in their neck and shoulders.

Learn more:  http://www.sciencedaily.com/releases/2009/11/091110105355.htm  

World Trade Center responders plagued with asthma:  Reported asthma in 9/11 responders 2X greater than general population

Responders to the 2001 World Trade Center (WTC) terrorist attacks, who were exposed to caustic dust and toxic pollutants following the 9/11 disaster, suffer from asthma at a rate more than twice that of the general US population, according to new research presented at CHEST 2009, the 75th annual international scientific assembly of the American College of Chest Physicians (ACCP).

As many as 8 percent of the workers and volunteers who engaged in rescue and recovery, essential service restoration, and cleanup efforts in the wake of 9/11 reported experiencing post-9/11 asthma attacks or episodes, compared with 4 percent of the general population. Furthermore, the lifetime prevalence of asthma in WTC responders was marked by a dramatic increase from 3 percent pre-9/11 to a high of 16 percent in each of the years from 2005 through 2007.

Read the full story:  http://www.eurekalert.org/pub_releases/2009-11/acoc-wtc102709.php


Wednesday, November 4, 2009
Dinner Meeting Presentation

AIDS in D.C.: Prevention, Detection, and Treatment

Has the AIDS epidemic subsided -  why don't we hear much about it anymore?  Do Occupational Health Nurses have any role in the national effort to combat Acquired Immune Deficiency Syndrome? We heard the answers to these questions and receivedt a comprehensive update on the status of HIV+ infections in the Metropolitan D.C. area.

Presented by Dr. Lisa Fitzpatrick, Infectious Disease Specialist who is the Director of the HIV clinic at Howard University and Director of the AIDS Education Training Center.

In this one hour lecture, Dr. Fitzpatrick updated our knowledge about treatment, prevention, and detection of this disease and how we can be more AIDS-Aware in our clinical practice.  1.0 Nursing CEU were awarded by the Juniper Program, funded by the federal Health Resource Services Administration.


Document
HIV Update: Occ Health Nurses 11-09
 

The Road to Hiroshima and Beyond

Amy Knowles, PhD, RN, MPH

This article is by an RN, Amy Knowles, with public health and emergency care experience who while participating in the University of Tennessee School of Nursing Department of Homeland Security Program, became aware of the U.S./Japan Radiation Effects Research Foundation and its work with survivors of the A-Bomb blasts of WWII.  This is an interesting description of the research she did in her dissertation.  The short PDF contains her story.  To learn more contact Dr. Knowles at:  aknowles@utk.edu

Document
The Road to Hiroshima and Beyond
 

Innovative Exercise Idea!


Think you might get funding to convert your staircases?
 
http://www.youtube.com/watch?v=xJMOI5_FKwg


 
 
Ms. Preeti Chandramani

Stress Management for OHNs

MWAOHN members had the pleasure of participating in a training activity by a gifted speaker on the topic of stress in nurses. The focus was on us as health professionals: how we help ourselves with new ways of stress reduction.

Ms. Preeti Chandramani, Masters of Science in Industrial Management and Masters of Arts in Organizational Psychology, conducted the training, entertaining us with many charming allegories and analogies from her ancestors and culture.

Ms. Chandramani helped us identify stressors, determine which we could manage, and interventions to help us become more resilient in our professional lives.

We highly recommend Ms. Chandramani if you are looking for a dynamic, interesting speaker for your organization.

To contact her:  preetht9@yahoo.com

Study Shows Common Pain Cream Could Protect Heart During Attack

CINCINNATI - New research from the University of Cincinnati shows that a common, over-the-counter pain salve rubbed on the skin during a heart attack could serve as a cardiac-protectant, preventing or reducing damage to the heart while interventions are administered.  They also found that a small incision made on the abdomen triggered an 81 percent reduction.  "Both this and the capsaicin effect are shown to work through similar neurological mechanisms," Keith Jones, PhD says. "These are the most powerful cardioprotective effects recorded to date. We think that this technique is fooling the body into sending out protective signals, Jones adds. This may be similar to the way certain acupuncture treatments work; there may be a neurological basis. In a broad sense, this work may provide a 'Rosetta stone' for translating alternative medicine techniques - like acupuncture - to Western medicine. Perhaps we can understand the biological mechanisms of how alternative treatments may be successful for patients."


Read more >>> http://healthnews.uc.edu/news/?/9213


Document
Institute of Medicine Healthcare Workers Respiratory Protection

A clue to the elusive cause of type 1 diabetes: Ottawa researchers investigate immune response to wheat

August 20, 2009  Scientists at the Ottawa Hospital Research Institute and the University of Ottawa have discovered what may be an important clue to the cause of type 1 diabetes. Dr. Fraser Scott and his team tested 42 people with type 1 diabetes and found that nearly half had an abnormal immune response to wheat proteins. The study is published in the August 2009 issue of the journal Diabetes.

Early in life, the immune system is supposed to learn to attack foreign invaders such as viruses and bacteria, while leaving the body's own tissues and harmless molecules in the environment alone (including food in the gut). When this process goes awry, autoimmune diseases and allergies can develop. Type 1 diabetes is an autoimmune disease that occurs when the immune system mistakenly attacks the pancreas, the organ that regulates blood sugar. Dr. Scott's research is the first to clearly show that immune cells called T cells from people with type 1 diabetes are also more likely to over-react to wheat. His research also shows that the over-reaction is linked to genes associated with type 1 diabetes.  Read more:   http://www.ohri.ca/newsroom/newsstory.asp?ID=189


Research shows why low vitamin D raises heart disease risks in diabetics

Aug. 21, 2009 -- Low levels of vitamin D are known to nearly double the risk of cardiovascular disease in patients with diabetes, and researchers at Washington University School of Medicine in St. Louis now think they know why.  They have found that diabetics deficient in vitamin D can't process cholesterol normally, so it builds up in their blood vessels, increasing the risk of heart attack and stroke. The new research has identified a mechanism linking low vitamin D levels to heart disease risk and may lead to ways to fix the problem, simply by increasing levels of vitamin Read more:  http://mednews.wustl.edu/news/page/normal/14489.html


Google Trends for Influenza - 2 Weeks Ahead of Official Reporting

Google tracks certain search terms that indicate increased interest in many topics.   http://www.google.com/insights/search/#. 

An important trend Google tracks is influenza.  Using their technology, they have found that Internet searches about influenza show increases in estimated flu activity about two weeks in advance of reports by CDC or other reporting organizations.  OHNs might want to periodically check this webpage to determine if influenza activity they are observing is also reflected in data from their state, the Nation, and around the World. 
http://www.google.org/flutrends/intl/en_us/

To learn how Google Trends works:  http://www.google.org/about/flutrends/how.html



Disaster Mental Health Recommendations from the HHS Office of the Assistant Secretary for Preparedness and Response:  November 2008

The Recommendations are:
  1. Integrate mental and behavioral health into all public health and medical preparedness and response activities.
  2. Enhance the research agenda for disaster mental and behavioral health.
  3. Enhance assessment of mental and behavioral health needs during emergencies.
  4. Enhance disaster mental and behavioral health training for professionals and paraprofessionals.
  5. Promote the population's psychological resilience.
  6. Ensure that the needs of at-risk individuals and issues of cultural responsiveness are being addressed in all efforts of the National Biodefense Science Board.
  7. Develop a disaster mental and behavioral health communication strategy.
  8. Develop an accessible Internet-based communication toolkit.
Read the entire report and action steps for implementing the recommendations at: 

http://www.hhs.gov/aspr/conferences/nbsb/dmhreport-final.pdf

Dye used to make Blue M&Ms and Blue Gatorade Linked to Reducing Spinal Cord Injury

The same blue food dye found in M&Ms and Gatorade could be used to reduce damage caused by spine injuries, offering a better chance of recovery, according to new research.  Researchers at the University of Rochester Medical Center found that when they injected the compound Brilliant Blue G (BBG) into rats suffering spinal cord injuries, the rodents were able to walk again, albeit with a limp.  The only side effect was that the treated mice temporarily turned blue.  The results of the study, published in the "Proceedings of the National Academy of Sciences," build on research conducted by the same center five years ago.  Read the story at:  http://www.pnas.org/content/106/30/12489
Normal and Blue Dyed Mouse

Study Explains Why Police Officers have a Higher Risk of Developing Heart Disease

In the most recent results coming out of one of the few long-term studies being conducted within this tightly knit society, University at Buffalo researchers have determined that underlying the higher incidence of subclinical atherosclerosis -- arterial thickening that precedes a heart attack or stroke - may be the stress of police work.

In the study from the University of Buffalo, accepted for publication in Psychiatry Research, that looked at the male-female differences in stress and signs of heart disease, researchers found that female police officers had higher levels of cortisol when they awoke, and the levels remained high throughout the day. Cortisol normally is highest in the morning and decreases to its lowest point in the evening. The constantly high cortisol levels were associated with less arterial elasticity, a risk factor for heart disease.

"When cortisol becomes dysregulated due to chronic stress, it opens a person to disease," John Violanti, Ph.D., UB associate professor of social and preventive medicine said.  "The body becomes physiologically unbalanced, organs are attacked and the immune system is compromised as well. It's unfortunate, but that's what stress does to us."

In the current study, the researchers used carotid artery thickness to assess heart disease risk. Participants were 322 clinically healthy active-duty police officers from the Buffalo Cardio-Metabolic Occupational Police Stress study and 318 healthy persons from the ongoing UB Western New York Health Study matched to the officers by age.

All measurements were taken in the morning after a 12-hour fast. In addition to testing carotid thickness via ultrasound, investigators measured blood pressure, body size, cholesterol (both total and HDL) and glucose. They collected information on physical activity, symptoms of depression, alcohol consumption and smoking history. These are the factors that typically cause heart disease.

Results showed that police work was associated with increased subclinical cardiovascular disease -- there was more plaque build-up in the carotid artery -- compared to the general population that could not be explained by those conventional heart disease risk factors.

Read more:  http://www.buffalo.edu/news/10220


Study Shows that Metformin Enhances Immune System

Researchers at McGill University and the University of Pennsylvania have discovered that a widely used anti-diabetic drug, metformin, can boost the immune system and increase the potency of vaccines and cancer treatments.  They discovered that the widely prescribed diabetes treatment metformin increases the efficiency of the immune system's T-cells, which in turn makes cancer and virus-fighting vaccines more effective.

"We serendipitously discovered that the metabolizing, or burning, of fatty acids by T-cells following the peak of infection is critical to establishing immunological memory," Pearce added. "We used metformin, which is known to operate on fatty-acid metabolism, to enhance this process, and have shown experimentally in mice that metformin increases T-cell memory as well as the ensuing protective immunity of an experimental anti-cancer vaccine."

Few talk about cancer and diabetes in the same breath. However, recent advances have uncovered common links between cancer and diabetes, in particular how metabolic pathways, the basic chemical reactions that happen in our cells, are controlled in these diseases. The recent findings suggest a new link between the metabolic pathways deregulated in cancer and diabetes and their role in immune cell function. The results suggest that common diabetic therapies which alter cellular metabolism may enhance T-cell memory, providing a boost to the immune system. This could lead to novel strategies for vaccine and anti-cancer therapies.

"Our findings were unanticipated, but are potentially extremely important and could revolutionize current strategies for both therapeutic and protective vaccines," Choi said.

Science Daily:  http://www.sciencedaily.com/releases/2009/06/090603131433.htm

Abstract:  http://www.nature.com/nature/journal/vaop/ncurrent/full/nature08097.html 

LEAN Works

Includes an Obesity Calculator!

In 2000, the total cost (direct and indirect) attributable to obesity was estimated to be $117 billion,1 and between 1987 and 2001, diseases associated with obesity accounted for 27 percent of the increases in medical costs.23 Medical expenses for obese employees are estimated to be between 29 percent and 117 percent greater than medical expenses for employees with a healthy weight.

What is the cost of obesity to your organization?

"CDC's LEAN Works! Leading Employees to Activity and Nutrition" is a FREE web-based resource that offers interactive tools and evidence-based resources to design effective worksite obesity prevention and control programs, including an obesity cost calculator to estimate how much obesity is costing your company and how much savings your company could reap with different workplace interventions.

Recommended by Wellness Program Manager at Brookhaven National Laboratory, Michael Thorn

http://www.cdc.gov/leanworks/

Study:  Lap Band Surgery for Obese Teens Results in Reduced Metabolic Syndrome Risk

"An estimated 17 percent of all American adolescents are obese, and increasing numbers of them also have metabolic syndrome," says Dr. Fennoy, a pediatric endocrinologist at NewYork-Presbyterian Morgan Stanley Children's Hospital, clinical professor of pediatrics at the Columbia University College of Physicians and Surgeons and co-author of the study. "Until recently, there have been few treatments capable of helping these young patients lose weight, much less improving their lifelong health prospects. The Lap-Band may well be a useful intervention for tackling teen obesity -- which is why it is so important to investigate the procedure's safety and efficacy in this growing population."

In the new study, Dr. Fennoy and her colleagues followed 24 morbidly obese adolescents between the ages of 14 and 17 who underwent the Lap-Band procedure. The study participants either had a BMI of greater than 40 or greater than 35 if already suffering from diabetes or obesity-related illnesses.

Six months after surgery, they noted a significant drop in participants' BMI, waist circumference, and blood levels of C-reactive protein. These indicators continued to improve among the 12 patients being followed up at the one-year point.

Other measures of metabolic syndrome such as blood lipid and sugar levels, the authors reported, came down quickly in the first six months, with "less dramatic" changes seen one year after surgery.


Read more: 
http://www.eurekalert.org/pub_releases/2009-07/nyph-lws070109.php

The Economic Impact of Pandemic Influenza in the United States: Priorities for  Intervention

OHNs may find this publication of use when writing justification for influenza immunization programs.

Martin I. Meltzer, Nancy J. Cox, and Keiji Fukuda
Centers for Disease Control and Prevention, Atlanta, Georgia, USA

Abstract:
We estimated the possible effects of the next influenza pandemic in the United States and analyzed the economic impact of vaccine-based interventions. Using death rates, hospitalization data, and outpatient visits, we estimated 89,000 to 207,000 deaths; 314,000 to 734,000 hospitalizations; 18 to 42 million outpatient visits; and 20 to 47 million additional illnesses. Patients at high risk (15% of the population) would account for approximately 84% of all deaths. The estimated economic impact would be US$71.3 to $166.5 billion, excluding disruptions to commerce and society. At $21 per vaccinee, we project a net savings to society if persons in all age groups are vaccinated. At $62 per vaccinee and at gross attack rates of 25%, we project net losses if persons not at high risk for complications are vaccinated. Vaccinating 60% of the population would generate the highest economic returns but may not be possible within the time required for vaccine effectiveness, especially if two doses of vaccine are required.

Full article:  http://www.cdc.gov/ncidod/eid/vol5no5/meltzer.htm

Pandemic Influenza:  Implications for Occupational Medicine

Abstract

This article reviews the biological and occupational medicine literature related to H5N1 pandemic influenza and its impact on infection control, cost and business continuity in settings outside the health care community. The literature on H5N1 biology is reviewed including the treatment and infection control mechanisms as they pertain to occupational medicine. Planning activity for the potential arrival of pandemic avian influenza is growing rapidly. Much has been published on the molecular biology of H5N1 but there remains a paucity of literature on the occupational medicine impacts to organizations. This review summarizes some of the basic science surrounding H5N1 influenza and raises some key concerns in pandemic planning for the occupational medicine professional. Workplaces other than health care settings will be impacted greatly by an H5N1 pandemic and the occupational physician will play an essential role in corporate preparation, response, and business continuity strategies.

The full article is available free at: http://www.occup-med.com/content/pdf/1745-6673-4-15.pdf

W. Shane Journeay*(1)   and   Matthew D. Burnstein (2)

1  Dalhousie Medical School, Dalhousie University, Faculty of Medicine, Halifax, Nova Scotia, B3H 4H7 Canada

2  Bell-Aliant Health & Wellness Division, 1505 Barrington Street,Halifax, Nova Scotia, B3J 3K5 Canada

E-mail:

*W. Shane Journeay: shane.journeay@dal.ca

Matthew D. Burnstein: matthew.burnstein@aliant.ca





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